A Better Approach To Process Analytical Technology and Impact of COVID-19……..

Posted by Mrudula Anil Karmarkar on January 16th, 2023

The global process analytical technology market is expected to reach USD 5.0 billion by 2030, according to a new report by Grand View Research, Inc., expanding at a CAGR of 10.2% from 2022 to 2030. The rising R&D spending by pharmaceutical companies, government investment in emerging markets, growing adherence to reliability by design (QbD) principles, increasing emphasis on improving quality and manufacturing process efficiency, and technological developments in the analytical technology industry are the main drivers in the market.

Process analytical technology is crucial to the manufacturing of pharmaceuticals as it provides data that aids in decision-making, quality assurance, product development, and factory implementation. Such technology also aids in spotting possible issues, such as contamination or foreign materials, in drug production procedures. Process analytical technology can detect contamination at levels as low as 0.1 parts per million, according to a report on the global process analytical technology. This could result in considerable time and financial savings and further boost the adoption of analytical technology in bioprocessing.

The COVID-19 pandemic has been a significant growth driver for several process analytical technology offerings. The search for efficient preventive and curative medications is intensifying in response to rising infection and mortality rates. Due to the fact that process analytical technology is largely used to monitor and assess the drug development process, demand for it significantly increased in 2020. For instance, in August 2022, as per the article published on InsideTele, modernizing synthesis workstations, offering precise reactor control, enabling the capture and digitalization of response process information, and securing the reproducibility as well as the link among users, experiments, and sites are all possible with the use of process analytical technology in drug formulation.

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It is anticipated that the adoption of new and better process analytical technology by key industry players will accelerate the expansion of the global market. For instance, in November 2021, Thermo Fisher Scientific launched MS & chromatography equipment during the Human Proteome Organization (HUPO) Reconnect event. For proteomics investigations, the high-resolution Thermo Scientific Orbitrap MS equipment is complemented by the Thermo Scientific Vanquish Neo UHPLC system, which reduces the loss of sample and produces data of the best possible quality. It is intended for high-sensitive LC-MS applications and has strong analytical efficiency at a rate of flow that ranges from 1 nL/min to 100 L/min up to 1,500 bar.

Process Analytical Technology Market Report Highlights

  • By product, the analyzers segment held the largest share in 2021. This is anticipated to be driven by the rising demand for the treatment of water and wastewater and increased use of process analyzers in medication safety
  • By technique, the spectroscopy segment captured a leading share in 2021. One of the main factors propelling the expansion of the spectroscopy segment is the rise in pharmaceutical and biopharmaceutical R&D activities and technological developments that lead to process optimization
  • By monitoring method, the in-line segment accounted for the largest share in 2021. The segment is being driven by the low turnaround times and consistency of results from the in-line analysis
  • By end-use, the pharmaceutical and biotechnology companies segment held the largest share in 2021. This can be attributed to the expanding biotechnology sector in both established and emerging nations and the rising need for biochemical analysis brought on by the approval and introduction of numerous biologic medications
  • North America dominated the market in 2021. The regional market is driven by an increase in R&D spending by pharmaceutical and biopharmaceutical organizations, increasing focus on quality and production, improved efficiency, growing ability to adhere to QbD principles by businesses operating in the region, and the availability of technologically advanced healthcare research framework
  • Asia Pacific is expected to expand at the highest rate over the projected period. This can be attributed to expanding government investment in the biotechnology sector, a rise in the number of contract research and manufacturing companies, and a growing concentration of global players in developing regions

The outbreak of the COVID-19 pandemic led to an upsurge in the use of PAT. The operating players in the advanced manufacturing division have introduced PAT to aid in the production of drugs and other essential products such as sanitizers, masks, and gloves. Moreover, the drug shortage observed during the COVID-19 pandemic has compelled pharmaceutical companies to focus on finding quicker ways to deliver medications by utilizing PAT.

The growing adoption of process analytical technology by the pharma and biotech industry is positively impacting the market growth. The incorporation of analyzers, sensors, probes, and software in industries can enhance product quality, reduce process costs, and ensure product safety. PAT also helps in eliminating product re-work, easing regulation compliance, and smoothening the process cycles. At the same time, this technology offers modern synthesis, transforms organizational productivity, provides insights for every reaction, takes control of crystallization, sustains a culture of safety, and delivers from lab to plant in the pharmaceutical sector. These advantages are likely to boost the implementation of process analytical technology and can drive the market during the forecast period.

List of Key Players in Process Analytical Technology Market

  • Thermo Fisher Scientific Inc.
  • Agilent Technologies, Inc.
  • Danaher Corporation (Ab Sciex LLC)
  • Bruker Corporation
  • PerkinElmer, Inc.
  • ABB Ltd.
  • Carl Zeiss AG (Zeiss Group)
  • Emerson Electric Co.
  • Mettler-Toledo
  • Shimadzu Corporation

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Mrudula Anil Karmarkar

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Mrudula Anil Karmarkar
Joined: July 2nd, 2020
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